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CMIP interacts with WT1 and targets it on the proteasome degradation pathway

BACKGROUND: The Wilms tumor 1 suppressor gene, WT1, is expressed throughout life in podocytes and is essential for their function. Downregulation of WT1 has been reported in podocyte diseases but the underlying mechanisms remain unclear. Podocyte injury is the hallmark of idiopathic nephrotic syndro...

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Detalles Bibliográficos
Autores principales: Zhang, Shao‐Yu, Fan, Qingfeng, Moktefi, Anissa, Ory, Virginie, Audard, Vincent, Pawlak, Andre, Ollero, Mario, Sahali, Dil, Henique, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299046/
https://www.ncbi.nlm.nih.gov/pubmed/34323419
http://dx.doi.org/10.1002/ctm2.460