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MCU-Dependent mROS Generation Regulates Cell Metabolism and Cell Death Modulated by the AMPK/PGC-1α/SIRT3 Signaling Pathway

The mitochondrial calcium uniporter is an intensively investigated calcium channel, and its molecular components, structural features, and encoded genes have long been explored. Further studies have shown that the mitochondrial calcium unidirectional transporter (MCU) is a macromolecular complex rel...

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Detalles Bibliográficos
Autores principales: Wang, Yuxin, Li, Xiang, Zhao, Fengchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299052/
https://www.ncbi.nlm.nih.gov/pubmed/34307407
http://dx.doi.org/10.3389/fmed.2021.674986