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Blockage of Drp1 phosphorylation at Ser579 protects neurons against Aβ(1–42)-induced degeneration
Alzheimer's disease (AD), one of the most common types of chronic neurodegenerative diseases, is pathologically characterized by the formation of amyloid β (Aβ) peptide-containing plaques and neurofibrillary tangles. Among Aβ peptides, Aβ(1–42) induces neuronal toxicity and neurodegeneration. I...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299198/ https://www.ncbi.nlm.nih.gov/pubmed/34278489 http://dx.doi.org/10.3892/mmr.2021.12296 |