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Blockage of Drp1 phosphorylation at Ser579 protects neurons against Aβ(1–42)-induced degeneration

Alzheimer's disease (AD), one of the most common types of chronic neurodegenerative diseases, is pathologically characterized by the formation of amyloid β (Aβ) peptide-containing plaques and neurofibrillary tangles. Among Aβ peptides, Aβ(1–42) induces neuronal toxicity and neurodegeneration. I...

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Detalles Bibliográficos
Autores principales: Xu, Dan, Yang, Ping, Yang, Zhang-Jian, Li, Qiu-Gen, Ouyang, Ye-Tong, Yu, Ting, Shangguan, Jian-Hui, Wan, Yu-Ying, Jiang, Li-Ping, Qu, Xin-Hui, Han, Xiao-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299198/
https://www.ncbi.nlm.nih.gov/pubmed/34278489
http://dx.doi.org/10.3892/mmr.2021.12296

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