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CTP promotes efficient ParB-dependent DNA condensation by facilitating one-dimensional diffusion from parS

Faithful segregation of bacterial chromosomes relies on the ParABS partitioning system and the SMC complex. In this work, we used single-molecule techniques to investigate the role of cytidine triphosphate (CTP) binding and hydrolysis in the critical interaction between centromere-like parS DNA sequ...

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Detalles Bibliográficos
Autores principales: Balaguer, Francisco de Asis, Aicart-Ramos, Clara, Fisher, Gemma LM, de Bragança, Sara, Martin-Cuevas, Eva M, Pastrana, Cesar L, Dillingham, Mark Simon, Moreno-Herrero, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299390/
https://www.ncbi.nlm.nih.gov/pubmed/34250901
http://dx.doi.org/10.7554/eLife.67554