Cargando…

Protecting Stem Cell Derived Pancreatic Beta-Like Cells From Diabetogenic T Cell Recognition

Type 1 diabetes results from an autoimmune attack directed at pancreatic beta cells predominantly mediated by T cells. Transplantation of stem cell derived beta-like cells (sBC) have been shown to rescue diabetes in preclinical animal models. However, how sBC will respond to an inflammatory environm...

Descripción completa

Detalles Bibliográficos
Autores principales: Castro-Gutierrez, Roberto, Alkanani, Aimon, Mathews, Clayton E., Michels, Aaron, Russ, Holger A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299417/
https://www.ncbi.nlm.nih.gov/pubmed/34305820
http://dx.doi.org/10.3389/fendo.2021.707881