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Protecting Stem Cell Derived Pancreatic Beta-Like Cells From Diabetogenic T Cell Recognition
Type 1 diabetes results from an autoimmune attack directed at pancreatic beta cells predominantly mediated by T cells. Transplantation of stem cell derived beta-like cells (sBC) have been shown to rescue diabetes in preclinical animal models. However, how sBC will respond to an inflammatory environm...
Autores principales: | Castro-Gutierrez, Roberto, Alkanani, Aimon, Mathews, Clayton E., Michels, Aaron, Russ, Holger A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299417/ https://www.ncbi.nlm.nih.gov/pubmed/34305820 http://dx.doi.org/10.3389/fendo.2021.707881 |
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