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Direct Synthesis of Enamides via Electrophilic Activation of Amides
[Image: see text] A novel, one-step N-dehydrogenation of amides to enamides is reported. This reaction employs the unlikely combination of LiHMDS and triflic anhydride, which serves as both the electrophilic activator and the oxidant, and is characterized by its simple setup and broad substrate scop...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299460/ https://www.ncbi.nlm.nih.gov/pubmed/34232035 http://dx.doi.org/10.1021/jacs.1c04363 |