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Emerging strategies to target RAS signaling in human cancer therapy

RAS mutations (HRAS, NRAS, and KRAS) are among the most common oncogenes, and around 19% of patients with cancer harbor RAS mutations. Cells harboring RAS mutations tend to undergo malignant transformation and exhibit malignant phenotypes. The mutational status of RAS correlates with the clinicopath...

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Detalles Bibliográficos
Autores principales: Chen, Kun, Zhang, Yalei, Qian, Ling, Wang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299671/
https://www.ncbi.nlm.nih.gov/pubmed/34301278
http://dx.doi.org/10.1186/s13045-021-01127-w