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Rewarding Subjective Effects of the NMDAR Antagonist Nitrous Oxide (Laughing Gas) Are Moderated by Impulsivity and Depressive Symptoms in Healthy Volunteers

BACKGROUND: Nitrous oxide (N(2)O) is an anesthetic gas with both therapeutic and abuse potential. Because N(2)O is an NMDA receptor (NMDAR) antagonist, its effects are expected to resemble those of the prototypical NMDAR antagonist, ketamine. In this study, we examined the subjective rewarding effec...

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Detalles Bibliográficos
Autores principales: Kamboj, Sunjeev K, Zhao, Hannah, Troebinger, Luzia, Piazza, Giulia, Cawley, Emma, Hennessy, Vanessa, Iskandar, Georges, Das, Ravi K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299821/
https://www.ncbi.nlm.nih.gov/pubmed/33667308
http://dx.doi.org/10.1093/ijnp/pyab009