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Targeting TL1A/DR3 Signaling Offers a Therapeutic Advantage to Neutralizing IL13/IL4Rα in Muco-Secretory Fibrotic Disorders

Mucus secretion is an important feature of asthma that highly correlates with morbidity. Current therapies, including administration of mucolytics and anti-inflammatory drugs, show limited effectiveness and durability, underscoring the need for novel effective and longer lasting therapeutic approach...

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Detalles Bibliográficos
Autores principales: Steele, Hope, Sachen, Kacey, McKnight, Andrew J., Soloff, Rachel, Herro, Rana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299868/
https://www.ncbi.nlm.nih.gov/pubmed/34305924
http://dx.doi.org/10.3389/fimmu.2021.692127