An N-ethyl-N-Nitrosourea Mutagenesis Screen in Mice Reveals a Mutation in Nuclear Respiratory Factor 1 (Nrf1) Altering the DNA Methylation State and Correct Embryonic Development

SIMPLE SUMMARY: In this work, we aimed to discover unknown genes that are important in the regulation of other genes. These genes often play an important role during the development of the embryo. By screening thousands of mice, we found a gene, namely, Nuclear Respiratory Factor 1 (Nrf1), that cont...

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Detalles Bibliográficos
Autores principales: Sorolla, Maria Alba, Marqués, Marta, Parisi, Eva, Sorolla, Anabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300126/
https://www.ncbi.nlm.nih.gov/pubmed/34359231
http://dx.doi.org/10.3390/ani11072103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300126/
https://www.ncbi.nlm.nih.gov/pubmed/34359231
http://dx.doi.org/10.3390/ani11072103

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