Nonlinear Mixed-Effect Pharmacokinetic Modeling and Distribution of Doxycycline in Healthy Female Donkeys after Multiple Intragastric Dosing–Preliminary Investigation

SIMPLE SUMMARY: Rational use of antibiotic is of most importance for human and animal health. Donkeys have differences in metabolism compared to horses, and drug dosage should not be extrapolated from horses’ data. Doxycycline, a common antibiotic used in equine medicine, has never been investigated...

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Detalles Bibliográficos
Autores principales: Chapuis, Ronan J. J., Smith, Joe S., French, Hilari M., Toka, Felix Ngosa, Peterson, Erik W., Little, Erika L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300337/
https://www.ncbi.nlm.nih.gov/pubmed/34359175
http://dx.doi.org/10.3390/ani11072047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300337/
https://www.ncbi.nlm.nih.gov/pubmed/34359175
http://dx.doi.org/10.3390/ani11072047

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