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Nonlinear Mixed-Effect Pharmacokinetic Modeling and Distribution of Doxycycline in Healthy Female Donkeys after Multiple Intragastric Dosing–Preliminary Investigation
SIMPLE SUMMARY: Rational use of antibiotic is of most importance for human and animal health. Donkeys have differences in metabolism compared to horses, and drug dosage should not be extrapolated from horses’ data. Doxycycline, a common antibiotic used in equine medicine, has never been investigated...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300337/ https://www.ncbi.nlm.nih.gov/pubmed/34359175 http://dx.doi.org/10.3390/ani11072047 |