Supervised Molecular Dynamics (SuMD) Insights into the mechanism of action of SARS-CoV-2 main protease inhibitor PF-07321332

The chemical structure of PF-07321332, the first orally available Covid-19 clinical candidate, has recently been revealed by Pfizer. No information has been provided about the interaction pattern between PF-07321332 and its biomolecular counterpart, the SARS-CoV-2 main protease (M(pro)). In the pres...

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Detalles Bibliográficos
Autores principales: Pavan, Matteo, Bolcato, Giovanni, Bassani, Davide, Sturlese, Mattia, Moro, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300928/
https://www.ncbi.nlm.nih.gov/pubmed/34289752
http://dx.doi.org/10.1080/14756366.2021.1954919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300928/
https://www.ncbi.nlm.nih.gov/pubmed/34289752
http://dx.doi.org/10.1080/14756366.2021.1954919

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