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Pharmacokinetic variables of medium molecular weight cross linked chitosan nanoparticles to enhance the bioavailability of 5-fluorouracil and reduce the acute oral toxicity

To prepare glutaraldehyde-based cross-linked medium molecular weight chitosan nanoparticles encapsulated with 5-Fluorouracil (5-FU), to overcome dosing frequency as well as reducing acute oral toxicity and poor bioavailability of the drug. Medium molecular weight chitosan nanoparticles (MMWCH-NPs) w...

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Detalles Bibliográficos
Autores principales: Sethi, Aisha, Ahmad, Mahmood, Huma, Tayyaba, Ahmad, Waqas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300936/
https://www.ncbi.nlm.nih.gov/pubmed/34291722
http://dx.doi.org/10.1080/10717544.2021.1944398