3H-1,2-Dithiole-3-Thione Protects Lens Epithelial Cells against Fructose-Induced Epithelial-Mesenchymal Transition via Activation of AMPK to Eliminate AKR1B1-Induced Oxidative Stress in Diabetes Mellitus

Studies demonstrated that the receptor of advanced glycation end products (RAGE) induced epithelial-mesenchymal transition (EMT) formation in the lens epithelial cells (LECs) of diabetic cataracts. This work investigated how 3H-1,2-dithiole-3-thione (D3T) reduces EMT formation in LECs of the fructos...

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Detalles Bibliográficos
Autores principales: Wu, Tsung-Tien, Chen, Ying-Ying, Ho, Chiu-Yi, Yeh, Tung-Chen, Sun, Gwo-Ching, Tseng, Ching-Jiunn, Cheng, Pei-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301018/
https://www.ncbi.nlm.nih.gov/pubmed/34356319
http://dx.doi.org/10.3390/antiox10071086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301018/
https://www.ncbi.nlm.nih.gov/pubmed/34356319
http://dx.doi.org/10.3390/antiox10071086

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