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Blood Pressure-Lowering Effect of Wine Lees Phenolic Compounds Is Mediated by Endothelial-Derived Factors: Role of Sirtuin 1

The antihypertensive effect of wine lees powder (WLPW) from a Cabernet grape variety was related to its high content in flavanols and anthocyanins compounds. This study investigates the involvement of endothelial-derived factors and SIRT1 in its bioactivity. Spontaneously hypertensive rats (SHR) wer...

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Detalles Bibliográficos
Autores principales: López-Fernández-Sobrino, Raúl, Soliz-Rueda, Jorge R., Ávila-Román, Javier, Arola-Arnal, Anna, Suárez, Manuel, Muguerza, Begoña, Bravo, Francisca Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301028/
https://www.ncbi.nlm.nih.gov/pubmed/34356306
http://dx.doi.org/10.3390/antiox10071073