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Reengineering Tumor Microenvironment with Sequential Interleukin Delivery

Some cytokines can reengineer anti-tumor immunity to modify the tumor micro-environment. Interleukin-27 (IL-27) can partially reduce tumor growth in several animal models, including prostate cancer. We hypothesized that addition of IL-18, which can induce the proliferation of several immune effector...

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Detalles Bibliográficos
Autores principales: Figueiredo, Marxa L., Letteri, Rachel, Chan-Seng, Delphine, Kumar, Shreya, Rivera-Cruz, Cosette M., Emrick, Todd S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301035/
https://www.ncbi.nlm.nih.gov/pubmed/34209203
http://dx.doi.org/10.3390/bioengineering8070090