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TGF-β1 Facilitates TAp63α Protein Lysosomal Degradation to Promote Pancreatic Cancer Cell Migration

SIMPLE SUMMARY: Numerous studies demonstrate that the activation of transforming growth factor-β (TGF-β) signaling is a critical driving force for promoting cancer cell migration and tumor metastasis. Our recent study indicates that TGF-β1 promotes FBXO3-mediated ΔNp63α protein degradation to facili...

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Detalles Bibliográficos
Autores principales: Gao, Guohui, Chen, Jie, Wang, Dongbo, Li, Qiao, Yang, Xiaojiao, Wang, Jindan, Pan, Zhiyong, Xiao, Zhi-Xiong Jim, Yi, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301043/
https://www.ncbi.nlm.nih.gov/pubmed/34203341
http://dx.doi.org/10.3390/biology10070597