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Failure of the Brain Glucagon-Like Peptide-1-Mediated Control of Intestinal Redox Homeostasis in a Rat Model of Sporadic Alzheimer’s Disease

The gastrointestinal system may be involved in the etiopathogenesis of the insulin-resistant brain state (IRBS) and Alzheimer’s disease (AD). Gastrointestinal hormone glucagon-like peptide-1 (GLP-1) is being explored as a potential therapy as activation of brain GLP-1 receptors (GLP-1R) exerts neuro...

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Detalles Bibliográficos
Autores principales: Homolak, Jan, Babic Perhoc, Ana, Knezovic, Ana, Osmanovic Barilar, Jelena, Salkovic-Petrisic, Melita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301063/
https://www.ncbi.nlm.nih.gov/pubmed/34356351
http://dx.doi.org/10.3390/antiox10071118