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Integration of Cardiac Actin Mutants Causing Hypertrophic (p.A295S) and Dilated Cardiomyopathy (p.R312H and p.E361G) into Cellular Structures

The human mutant cardiac α-actins p.A295S or p.R312H and p.E361G, correlated with hypertrophic or dilated cardiomyopathy, respectively, were expressed by the baculovirus/Sf21 insect cell system and purified to homogeneity. The purified cardiac actins maintained their native state but showed differen...

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Detalles Bibliográficos
Autores principales: Erdmann, Constanze, Hassoun, Roua, Schmitt, Sebastian, Kikuti, Carlos, Houdusse, Anne, Mazur, Antonina J., Mügge, Andreas, Hamdani, Nazha, Geyer, Matthias, Jaquet, Kornelia, Mannherz, Hans Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301065/
https://www.ncbi.nlm.nih.gov/pubmed/34356314
http://dx.doi.org/10.3390/antiox10071082