Oxidative Stress and Mitochondrial Damage in Dry Age-Related Macular Degeneration Like NFE2L2/PGC-1α (-/-) Mouse Model Evoke Complement Component C5a Independent of C3

SIMPLE SUMMARY: Age-related macular degeneration (AMD) is an eye disease that results in permanent loss of vision due to degeneration in the central portion of the retina called the macula. Patients with severe visual loss have reduced quality of life and the risk of death is 2.4 times higher than t...

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Detalles Bibliográficos
Autores principales: Sridevi Gurubaran, Iswariyaraja, Heloterä, Hanna, Marry, Stephen, Koskela, Ali, Hyttinen, Juha M. T., Paterno, Jussi J., Urtti, Arto, Chen, Mei, Xu, Heping, Kauppinen, Anu, Kaarniranta, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301195/
https://www.ncbi.nlm.nih.gov/pubmed/34356477
http://dx.doi.org/10.3390/biology10070622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301195/
https://www.ncbi.nlm.nih.gov/pubmed/34356477
http://dx.doi.org/10.3390/biology10070622

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