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Translational neurophysiological biomarkers of N-methyl-d-aspartate receptor dysfunction in serine racemase knockout mice

Alterations in glutamatergic function are well established in schizophrenia (Sz), but new treatment development is hampered by the lack of translational pathophysiological and target engagement biomarkers as well as by the lack of animal models that recapitulate the pathophysiological features of Sz...

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Detalles Bibliográficos
Autores principales: Balla, Andrea, Ginsberg, Stephen D., Abbas, Atheir I., Sershen, Henry, Javitt, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301266/
https://www.ncbi.nlm.nih.gov/pubmed/34308374
http://dx.doi.org/10.1016/j.bionps.2020.100019