Fine-Tuning the PI3K/Akt Signaling Pathway Intensity by Sex and Genotype-Load: Sex-Dependent Homozygotic Threshold for Somatic Growth but Feminization of Anxious Phenotype in Middle-Aged PDK1 K465E Knock-In and Heterozygous Mice

According to the Research Domain Criteria (RDoC), phenotypic differences among disorders may be explained by variations in the nature and degree of neural circuitry disruptions and/or dysfunctions modulated by several biological and environmental factors. We recently demonstrated the in vivo behavio...

Descripción completa

Detalles Bibliográficos
Autores principales: Santana-Santana, Mikel, Bayascas, José-Ramón, Giménez-Llort, Lydia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301321/
https://www.ncbi.nlm.nih.gov/pubmed/34203450
http://dx.doi.org/10.3390/biomedicines9070747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301321/
https://www.ncbi.nlm.nih.gov/pubmed/34203450
http://dx.doi.org/10.3390/biomedicines9070747

Ejemplares similares