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Stable Gastric Pentadecapeptide BPC 157 Therapy for Monocrotaline-Induced Pulmonary Hypertension in Rats Leads to Prevention and Reversal

Background. Monocrotaline selectively injures the lung’s vascular endothelium and induces pulmonary arterial hypertension. The stable gastric pentadecapeptide BPC 157 acts as a prototype cytoprotective agent that maintains endothelium, and its application may be a novel therapy. Besides, BPC 157 pre...

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Detalles Bibliográficos
Autores principales: Udovicic, Mario, Sever, Marko, Kavur, Lovro, Loncaric, Kristina, Barisic, Ivan, Balenovic, Diana, Zivanovic Posilovic, Gordana, Strinic, Dean, Uzun, Sandra, Batelja Vuletic, Lovorka, Sikiric, Suncana, Skrtic, Anita, Drmic, Domagoj, Boban Blagaic, Alenka, Lovric Bencic, Martina, Seiwerth, Sven, Sikiric, Predrag
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301325/
https://www.ncbi.nlm.nih.gov/pubmed/34356886
http://dx.doi.org/10.3390/biomedicines9070822