Comparison of Linear vs. Cyclic RGD Pentapeptide Interactions with Integrin α(v)β(3) by Molecular Dynamics Simulations

SIMPLE SUMMARY: The integrin α(v)β(3)-RGD motif interaction plays a key role in the progression of malignant tumor. Although two typical cyclic and linear RGD short peptides have been widely used in tumor diagnosis and therapy, little is known about the internal dynamic mechanism for different confi...

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Detalles Bibliográficos
Autores principales: Li, Na, Qiu, Simei, Fang, Ying, Wu, Jianhua, Li, Quhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301328/
https://www.ncbi.nlm.nih.gov/pubmed/34356543
http://dx.doi.org/10.3390/biology10070688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301328/
https://www.ncbi.nlm.nih.gov/pubmed/34356543
http://dx.doi.org/10.3390/biology10070688

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