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In Vitro Evaluation of a Nanoparticle-Based mRNA Delivery System for Cells in the Joint

Biodegradable and bioresponsive polymer-based nanoparticles (NPs) can be used for oligonucleotide delivery, making them a promising candidate for mRNA-based therapeutics. In this study, we evaluated and optimized the efficiency of a cationic, hyperbranched poly(amidoamine)s-based nanoparticle system...

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Detalles Bibliográficos
Autores principales: Sturm, Lisa, Schwemberger, Bettina, Menzel, Ursula, Häckel, Sonja, Albers, Christoph E., Plank, Christian, Rip, Jaap, Alini, Mauro, Traweger, Andreas, Grad, Sibylle, Basoli, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301349/
https://www.ncbi.nlm.nih.gov/pubmed/34356857
http://dx.doi.org/10.3390/biomedicines9070794