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TLR7 Activation of Macrophages by Imiquimod Inhibits HIV Infection through Modulation of Viral Entry Cellular Factors

SIMPLE SUMMARY: The Toll-like receptor (TLR) 7 is highly expressed by immune cells including macrophages. Agonists to TLR7 are attractive therapeutic agents as they have the potential of activating both innate and acquired immunity against viral infections. Imiquimod, a specific TLR7 agonist, has be...

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Detalles Bibliográficos
Autores principales: Meng, Feng-Zhen, Liu, Jin-Biao, Wang, Xu, Wang, Peng, Hu, Wen-Hui, Hou, Wei, Ho, Wen-Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301371/
https://www.ncbi.nlm.nih.gov/pubmed/34356516
http://dx.doi.org/10.3390/biology10070661