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TLR7 Activation of Macrophages by Imiquimod Inhibits HIV Infection through Modulation of Viral Entry Cellular Factors
SIMPLE SUMMARY: The Toll-like receptor (TLR) 7 is highly expressed by immune cells including macrophages. Agonists to TLR7 are attractive therapeutic agents as they have the potential of activating both innate and acquired immunity against viral infections. Imiquimod, a specific TLR7 agonist, has be...
Autores principales: | Meng, Feng-Zhen, Liu, Jin-Biao, Wang, Xu, Wang, Peng, Hu, Wen-Hui, Hou, Wei, Ho, Wen-Zhe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301371/ https://www.ncbi.nlm.nih.gov/pubmed/34356516 http://dx.doi.org/10.3390/biology10070661 |
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