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TRPV1 Blocker HCRG21 Suppresses TNF-α Production and Prevents the Development of Edema and Hypersensitivity in Carrageenan-Induced Acute Local Inflammation

Currently the TRPV1 (transient receptor potential vanilloid type 1) channel is considered to be one of the main targets for pro-inflammatory mediators including TNF-α. Similarly, the inhibition of TRPV1 activity in the peripheral nervous system affects pro-inflammatory mediator production and enhanc...

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Detalles Bibliográficos
Autores principales: Sintsova, Oksana, Gladkikh, Irina, Klimovich, Anna, Palikova, Yulia, Palikov, Viktor, Styshova, Olga, Monastyrnaya, Margarita, Dyachenko, Igor, Kozlov, Sergey, Leychenko, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301426/
https://www.ncbi.nlm.nih.gov/pubmed/34201624
http://dx.doi.org/10.3390/biomedicines9070716