Cargando…
TRPV1 Blocker HCRG21 Suppresses TNF-α Production and Prevents the Development of Edema and Hypersensitivity in Carrageenan-Induced Acute Local Inflammation
Currently the TRPV1 (transient receptor potential vanilloid type 1) channel is considered to be one of the main targets for pro-inflammatory mediators including TNF-α. Similarly, the inhibition of TRPV1 activity in the peripheral nervous system affects pro-inflammatory mediator production and enhanc...
Autores principales: | Sintsova, Oksana, Gladkikh, Irina, Klimovich, Anna, Palikova, Yulia, Palikov, Viktor, Styshova, Olga, Monastyrnaya, Margarita, Dyachenko, Igor, Kozlov, Sergey, Leychenko, Elena |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301426/ https://www.ncbi.nlm.nih.gov/pubmed/34201624 http://dx.doi.org/10.3390/biomedicines9070716 |
Ejemplares similares
-
Kunitz-Type Peptide HCRG21 from the Sea Anemone Heteractis crispa Is a Full Antagonist of the TRPV1 Receptor
por: Monastyrnaya, Margarita, et al.
Publicado: (2016) -
New Kunitz-Type HCRG Polypeptides from the Sea Anemone Heteractis crispa
por: Gladkikh, Irina, et al.
Publicado: (2015) -
Kunitz-Type Peptides from the Sea Anemone Heteractis crispa Demonstrate Potassium Channel Blocking and Anti-Inflammatory Activities
por: Gladkikh, Irina, et al.
Publicado: (2020) -
Anti-Inflammatory and Analgesic Effects of TRPV1 Polypeptide Modulator APHC3 in Models of Osteo- and Rheumatoid Arthritis
por: Logashina, Yulia A., et al.
Publicado: (2021) -
Magnificamide, a β-Defensin-Like Peptide from the Mucus of the Sea Anemone Heteractis magnifica, Is a Strong Inhibitor of Mammalian α-Amylases
por: Sintsova, Oksana, et al.
Publicado: (2019)