IDH Mutations in Glioma: Double-Edged Sword in Clinical Applications?

Discovery of point mutations in the genes encoding isocitrate dehydrogenases (IDH) in gliomas about a decade ago has challenged our view of the role of metabolism in tumor progression and provided a new stratification strategy for malignant gliomas. IDH enzymes catalyze the conversion of isocitrate...

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Detalles Bibliográficos
Autores principales: Kayabolen, Alisan, Yilmaz, Ebru, Bagci-Onder, Tugba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301439/
https://www.ncbi.nlm.nih.gov/pubmed/34356864
http://dx.doi.org/10.3390/biomedicines9070799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301439/
https://www.ncbi.nlm.nih.gov/pubmed/34356864
http://dx.doi.org/10.3390/biomedicines9070799

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