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A population pharmacodynamic Markov mixed‐effects model for determining remimazolam‐induced sedation when co‐administered with fentanyl in procedural sedation

The clinical effects of remimazolam (an investigational, ultra‐short acting benzodiazepine being studied in procedural sedation) were measured using the Modified Observer’s Assessment of Awareness/Sedation Scale (MOAA/S). The objective of this analysis was to develop a population pharmacokinetic/pha...

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Detalles Bibliográficos
Autores principales: Zhou, Jie, Curd, Laura, Lohmer, Lauren R. L., Delpratt, Natalie, Ossig, Joachim, Schippers, Frank, Stoehr, Thomas, Schmith, Virginia D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301564/
https://www.ncbi.nlm.nih.gov/pubmed/33768731
http://dx.doi.org/10.1111/cts.13023