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Beyond exposure‐response: A tutorial on statistical considerations in dose‐ranging studies

Dose‐ranging studies are a crucial part of the phase II drug development process. They complement the understanding gained from exposure‐response analyses. However, the statistical design issues related to dose‐ranging studies are not always keenly understood and a poorly designed study can be costl...

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Detalles Bibliográficos
Autores principales: Laird, Glen, Xu, Lei, Liu, Meng, Liu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301570/
https://www.ncbi.nlm.nih.gov/pubmed/33650283
http://dx.doi.org/10.1111/cts.12998