A pharmacokinetic simulation study to assess the performance of a sparse blood sampling approach to quantify early drug exposure

Estimating early exposure of drugs used for the treatment of emergent conditions is challenging because blood sampling to measure concentrations is difficult. The objective of this work was to evaluate predictive performance of two early concentrations and prior pharmacokinetic (PK) information for...

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Detalles Bibliográficos
Autores principales: Sathe, Abhishek G., Brundage, Richard C., Ivaturi, Vijay, Cloyd, James C., Chamberlain, James M., Elm, Jordan J., Silbergleit, Robert, Kapur, Jaideep, Coles, Lisa D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301574/
https://www.ncbi.nlm.nih.gov/pubmed/33742783
http://dx.doi.org/10.1111/cts.13004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301574/
https://www.ncbi.nlm.nih.gov/pubmed/33742783
http://dx.doi.org/10.1111/cts.13004

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