A metabolomic analysis of thiol response for standard and modified N‐acetyl cysteine treatment regimens in patients with acetaminophen overdose

N‐acetylcysteine (NAC) is an antidote to prevent acetaminophen (paracetamol‐APAP)‐induced acute liver injury (ALI). The 3‐bag licensed 20.25 h standard regimen, and a 12 h modified regimen, are used to treat APAP overdose. This study evaluated the redox thiol response and APAP metabolites, in patien...

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Detalles Bibliográficos
Autores principales: Dear, James W, Ng, Mei Li, Bateman, D. Nicholas, Leroy Sivappiragasam, Pakkiri, Choi, Hyungwon, Khoo, Benjamin Bing Jie, Ibrahim, Baharudin, Drum, Chester Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301594/
https://www.ncbi.nlm.nih.gov/pubmed/33742775
http://dx.doi.org/10.1111/cts.13009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301594/
https://www.ncbi.nlm.nih.gov/pubmed/33742775
http://dx.doi.org/10.1111/cts.13009

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