Population pharmacokinetic analysis of apomorphine sublingual film or subcutaneous apomorphine in healthy subjects and patients with Parkinson’s disease

Apomorphine is an on‐demand treatment of “OFF” episodes in patients with Parkinson’s disease (PD). A joint parent‐metabolite population pharmacokinetic (PK) model characterized apomorphine and apomorphine‐sulfate following administration of apomorphine sublingual film (APL) and two formulations of s...

Descripción completa

Detalles Bibliográficos
Autores principales: Agbo, Felix, Crass, Ryan L., Chiu, Yu‐Yuan, Chapel, Sunny, Galluppi, Gerald, Blum, David, Navia, Bradford
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301595/
https://www.ncbi.nlm.nih.gov/pubmed/33650272
http://dx.doi.org/10.1111/cts.13008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301595/
https://www.ncbi.nlm.nih.gov/pubmed/33650272
http://dx.doi.org/10.1111/cts.13008

Ejemplares similares