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Population pharmacokinetic analysis of apomorphine sublingual film or subcutaneous apomorphine in healthy subjects and patients with Parkinson’s disease
Apomorphine is an on‐demand treatment of “OFF” episodes in patients with Parkinson’s disease (PD). A joint parent‐metabolite population pharmacokinetic (PK) model characterized apomorphine and apomorphine‐sulfate following administration of apomorphine sublingual film (APL) and two formulations of s...
Autores principales: | Agbo, Felix, Crass, Ryan L., Chiu, Yu‐Yuan, Chapel, Sunny, Galluppi, Gerald, Blum, David, Navia, Bradford |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301595/ https://www.ncbi.nlm.nih.gov/pubmed/33650272 http://dx.doi.org/10.1111/cts.13008 |
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