Treponema denticola dentilisin triggered TLR2/MyD88 activation upregulates a tissue destructive program involving MMPs via Sp1 in human oral cells

Periodontal disease is driven by dysbiosis in the oral microbiome, resulting in over-representation of species that induce the release of pro-inflammatory cytokines, chemokines, and tissue-remodeling matrix metalloproteinases (MMPs) in the periodontium. These chronic tissue-destructive inflammatory...

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Detalles Bibliográficos
Autores principales: Ganther, Sean, Radaic, Allan, Malone, Erin, Kamarajan, Pachiyappan, Chang, Nai-Yuan Nicholas, Tafolla, Christian, Zhan, Ling, Fenno, J. Christopher, Kapila, Yvonne L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301614/
https://www.ncbi.nlm.nih.gov/pubmed/34255809
http://dx.doi.org/10.1371/journal.ppat.1009311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301614/
https://www.ncbi.nlm.nih.gov/pubmed/34255809
http://dx.doi.org/10.1371/journal.ppat.1009311

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