Removal of peptidoglycan and inhibition of active cellular processes leads to daptomycin tolerance in Enterococcus faecalis

Daptomycin is a cyclic lipopeptide antibiotic used in the clinic for treatment of severe enterococcal infections. Recent reports indicate that daptomycin targets active cellular processes, specifically, peptidoglycan biosynthesis. Within, we examined the efficacy of daptomycin against Enterococcus f...

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Detalles Bibliográficos
Autores principales: Johnston, Rachel D., Woodall, Brittni M., Harrison, Johnathan, Campagna, Shawn R., Fozo, Elizabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301656/
https://www.ncbi.nlm.nih.gov/pubmed/34297729
http://dx.doi.org/10.1371/journal.pone.0254796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301656/
https://www.ncbi.nlm.nih.gov/pubmed/34297729
http://dx.doi.org/10.1371/journal.pone.0254796

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