Stop Codon Context-Specific Induction of Translational Readthrough

Premature termination codon (PTC) mutations account for approximately 10% of pathogenic variants in monogenic diseases. Stimulation of translational readthrough, also known as stop codon suppression, using translational readthrough-inducing drugs (TRIDs) may serve as a possible therapeutic strategy...

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Detalles Bibliográficos
Autores principales: Schilff, Mirco, Sargsyan, Yelena, Hofhuis, Julia, Thoms, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301745/
https://www.ncbi.nlm.nih.gov/pubmed/34356630
http://dx.doi.org/10.3390/biom11071006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301745/
https://www.ncbi.nlm.nih.gov/pubmed/34356630
http://dx.doi.org/10.3390/biom11071006

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