Cargando…
Stop Codon Context-Specific Induction of Translational Readthrough
Premature termination codon (PTC) mutations account for approximately 10% of pathogenic variants in monogenic diseases. Stimulation of translational readthrough, also known as stop codon suppression, using translational readthrough-inducing drugs (TRIDs) may serve as a possible therapeutic strategy...
Autores principales: | Schilff, Mirco, Sargsyan, Yelena, Hofhuis, Julia, Thoms, Sven |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301745/ https://www.ncbi.nlm.nih.gov/pubmed/34356630 http://dx.doi.org/10.3390/biom11071006 |
Ejemplares similares
-
Peroxisomal lactate dehydrogenase is generated by translational readthrough in mammals
por: Schueren, Fabian, et al.
Publicado: (2014) -
Heterologous Stop Codon Readthrough of Metazoan Readthrough Candidates in Yeast
por: Chan, Clara S., et al.
Publicado: (2013) -
Pseudouridine-mediated stop codon readthrough in S. cerevisiae is sequence context–independent
por: Adachi, Hironori, et al.
Publicado: (2020) -
Stop codon context influences genome-wide stimulation of termination codon readthrough by aminoglycosides
por: Wangen, Jamie R, et al.
Publicado: (2020) -
A reporter system for translational readthrough of stop codons in human cells
por: Halvey, Patrick J., et al.
Publicado: (2012)