Pitfalls of NMDA Receptor Modulation by Neuroactive Steroids. The Effect of Positive and Negative Modulation of NMDA Receptors in an Animal Model of Schizophrenia

Evidence from clinical and preclinical studies implicates dysfunction of N-methyl-D-aspartate receptors (NMDARs) in schizophrenia progression and symptoms. We investigated the antipsychotic effect of two neuroactive steroids in an animal model of schizophrenia induced by systemic application of MK-8...

Descripción completa

Detalles Bibliográficos
Autores principales: Holubova, Kristina, Chvojkova, Marketa, Hrcka Krausova, Barbora, Vyklicky, Vojtech, Kudova, Eva, Chodounska, Hana, Vyklicky, Ladislav, Vales, Karel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301783/
https://www.ncbi.nlm.nih.gov/pubmed/34356650
http://dx.doi.org/10.3390/biom11071026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301783/
https://www.ncbi.nlm.nih.gov/pubmed/34356650
http://dx.doi.org/10.3390/biom11071026

Ejemplares similares