Single Domain Antibodies as Carriers for Intracellular Drug Delivery: A Proof of Principle Study

Antibody-drug conjugates (ADCs) are currently used for the targeted delivery of drugs to diseased cells, but intracellular drug delivery and therefore efficacy may be suboptimal because of the large size, slow internalization and ineffective intracellular trafficking of the antibody. Using a phage d...

Descripción completa

Detalles Bibliográficos
Autores principales: Pronk, Sebas D., Schooten, Erik, Heinen, Jurgen, Helfrich, Esra, Oliveira, Sabrina, van Bergen en Henegouwen, Paul M. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301836/
https://www.ncbi.nlm.nih.gov/pubmed/34206656
http://dx.doi.org/10.3390/biom11070927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301836/
https://www.ncbi.nlm.nih.gov/pubmed/34206656
http://dx.doi.org/10.3390/biom11070927

Ejemplares similares