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Single Domain Antibodies as Carriers for Intracellular Drug Delivery: A Proof of Principle Study
Antibody-drug conjugates (ADCs) are currently used for the targeted delivery of drugs to diseased cells, but intracellular drug delivery and therefore efficacy may be suboptimal because of the large size, slow internalization and ineffective intracellular trafficking of the antibody. Using a phage d...
Autores principales: | Pronk, Sebas D., Schooten, Erik, Heinen, Jurgen, Helfrich, Esra, Oliveira, Sabrina, van Bergen en Henegouwen, Paul M. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301836/ https://www.ncbi.nlm.nih.gov/pubmed/34206656 http://dx.doi.org/10.3390/biom11070927 |
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