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Molecular Basis for Mechanical Properties of ECMs: Proposed Role of Fibrillar Collagen and Proteoglycans in Tissue Biomechanics

Collagen and proteoglycans work in unison in the ECM to bear loads, store elastic energy and then dissipate excess energy to avoid tissue fatigue and premature mechanical failure. While collagen fibers store elastic energy by stretching the flexible regions in the triple helix, they do so by lowerin...

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Detalles Bibliográficos
Autores principales: Silver, Frederick H., Kelkar, Nikita, Deshmukh, Tanmay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301845/
https://www.ncbi.nlm.nih.gov/pubmed/34356642
http://dx.doi.org/10.3390/biom11071018