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Acute MPTP Treatment Impairs Dendritic Spine Density in the Mouse Hippocampus

Among the animal models of Parkinson’s disease (PD), the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned mouse model has shown both dopaminergic (DA) damage and related motor control defects, as observed in patients with PD. Recent studies have suggested that the DA system interacts wit...

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Detalles Bibliográficos
Autores principales: Weerasinghe-Mudiyanselage, Poornima D. E., Ang, Mary Jasmin, Wada, Mai, Kim, Sung-Ho, Shin, Taekyun, Yang, Miyoung, Moon, Changjong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301854/
https://www.ncbi.nlm.nih.gov/pubmed/34201837
http://dx.doi.org/10.3390/brainsci11070833