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α-Synuclein Strains: Does Amyloid Conformation Explain the Heterogeneity of Synucleinopathies?
Synucleinopathies are a heterogeneous group of neurodegenerative diseases with amyloid deposits that contain the α-synuclein (SNCA/α-Syn) protein as a common hallmark. It is astonishing that aggregates of a single protein are able to give rise to a whole range of different disease manifestations. Th...
Autores principales: | Hoppe, Simon Oliver, Uzunoğlu, Gamze, Nussbaum-Krammer, Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301881/ https://www.ncbi.nlm.nih.gov/pubmed/34201558 http://dx.doi.org/10.3390/biom11070931 |
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