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Prion-Like Proteins in Phase Separation and Their Link to Disease

Aberrant protein folding underpins many neurodegenerative diseases as well as certain myopathies and cancers. Protein misfolding can be driven by the presence of distinctive prion and prion-like regions within certain proteins. These prion and prion-like regions have also been found to drive liquid-...

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Detalles Bibliográficos
Autores principales: Sprunger, Macy L., Jackrel, Meredith E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301953/
https://www.ncbi.nlm.nih.gov/pubmed/34356638
http://dx.doi.org/10.3390/biom11071014